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With technological advances, numerous redox sensors have been detected and identified

The general reaction involves formation of an unsymmetrical disulfide from the protectable protein (RSH) and GSH: [24] RSH + GSH + [O] GSSR + H 2 O Glutathione is also employed for the detoxification of methylglyoxal and formaldehyde, toxic metabolites produced under oxidative stress

Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimers pathologies

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On the other hand, the upregulation of TNF- in endothelial cells promotes cytoskeletal rearrangement, thereby compromising tight junction integrity and disrupting the structural cohesion of the basement membrane (37)

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