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First, managing side effects

The intake of L-carnitine can also reduce the feeling of exhaustion during physical exertion

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crassa The heterologous expression of the genes for the fullL-carnitine biosynthesis cascade by the plasmid pTrc99A-TML2Car revealed L-carnitine production not only from the supplemented precursor TML, but also without it, providing evidence of de novo L-carnitine biosynthesis (Figure 5)