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These drugs mimic the action of naturally occurring GLP-1, a hormone produced in the intestine that plays a crucial role in glucose regulation and appetite control

Natural GLP-1 Release: Oral D-allulose triggers the release of GLP-1 (glucagon-like peptide-1), a key hormone for satiety and glucose control, from the gut

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54,55 Within adaptive immunity, SIRT1 is essential for T cell activation and peripheral tolerance, preventing autoimmune diseases by suppressing AP-1 transcription and IL-2 production in the absence of CD28 costimulation