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These plaintiffs alleged that the manufacturer failed to warn about the increased risk of suicide when taking the drug

Gastrointestinal: Nausea, diarrhea, constipation, reduced appetite, acid reflux General: Fatigue during titration, injection site reactions Less Common: Headache, dizziness, elevated heart rate Slower titration helps those who experience significant nausea

This opened the door for more of these GLP-1 receptor agonists

However, users who implemented the meal timing and sleep hygiene strategies at earlier doses typically tolerate escalation better

Neuromethods 57:13-26

European regulators (EMA) follow a similar timeline