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In patients with T1D, adding semaglutide to insulin therapy may provide additional longterm protection against retinopathy
Since the relationship remains unclear, both the Endocrinologic and Metabolic Drugs Advisory Committee and the FDAs Division of Metabolism and Endocrinology Products concluded that there is not sufficient evidence available to conclude that incretin-based therapies cause acute pancreatitis or pancreatic cancer (65)
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This contrasts findings from another study showing that ANCOVA-adjusted EE is not different between vehicle- and semaglutide-treated mice with lean mass being used as a covariate [8]
Jameson JM, Cauvi G, Sharp LL, Witherden DA, Havran WL
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