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A higher level of fatty acids in plasma could be associated with cancer growth, which could be used to supply important energy sources, maintain the lipid bilayer structure of cancer cells, and transduce oncogenic signals (75, 76)

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Determining whether it is related to a specific drug versus weight change, nutrition, or other factors requires clinical evaluation and patient-specific context

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These include: Nausea (the most frequently reported adverse effect) Vomiting Diarrhoea Constipation Decreased appetite (which, while contributing to weight loss, can occasionally be excessive) These effects were generally mild to moderate in severity and occurred most frequently during the dose-escalation phase

Most were white and female