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And deubiquitinase (DUB) stabilizes intracellular protein structure by removing ubiquitin chains from ubiquitinated proteins

So the strongest neuroregenerative claims attributed to TB-500 are, strictly, claims about its parent protein component-level evidence, not direct evidence for the fragment

Some data suggest the peptide helps maintain cellular homeostasis by transporting copper through reversible redox cycling and ligand exchange [2]

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REU, reticular, erythematous, and ulceration

doi:10.1089/acm.2011.0503, PMID: 22757691 Ding W, Liu Y (2011) Genistein attenuates genioglossus muscle fatigue under chronic intermittent hypoxia by down-regulation of oxidative stress level and up-regulation of antioxidant enzyme activity through ERK1/2 signaling pathway