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SKU: 12296928772

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Description

DES(1-3) IGF-1 signals through the same IGF1R PI3K/AKT and MAPK/ERK axes as IGF-1 LR3 but, because it lacks the N-terminal extension that confers extended half-life in LR3, its circulating stability is more comparable to native IGF-1

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Proc Natl Acad Sci U S A 104(49):1934519350

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