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Weight Loss Results In the landmark SURMOUNT-1 trial, participants without diabetes achieved jaw-dropping weight loss results averaging 15-20% of their body weight over 72 weeks

However, the trial was neither powered nor designed to detect differences in MACE, and the follow-up duration was insufficient to draw long-term conclusions

Then tirzepatide showed up and stole its thunder

There isn't a lot of research on the health effects of periodic use, though other studies show weight regain after stopping GLP-1s is faster compared to other diets that focus on behavior changes

Monitoring: Key Health Markers to Track Regular monitoring ensures the stack is working as intended and catches potential issues before they become problems

Recognizing side effects as they happen is only part of the problem