Microdosing involves using doses below manufacturer-recommended levels without supporting clinical trial data on efficacy or safety
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Some GLP-1 agonists, like semaglutide and high-dose liraglutide, are also FDA-approved for treating obesity
However, a large Taiwanese cohort study of 11.7 million obese individuals found that GLP-1 RAs, particularly semaglutide, were associated with increased risk of depression, anxiety, and suicidal behavior [10]
Also, Nooms robust GLP-1 support enables clinical care and a personalized healthy habit and coaching program
While both regular dosing and microdosing utilize the same medications, their management approaches differ