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In practice, these differences are minor

It frames allulose as a food ingredient with modest metabolic effects and GLP-1 agonists as pharmaceutical interventions with potent systemic signaling

10.1021/bi2013454

This longitudinal observational study monitored Akkermansia levels in the gut microbiome of obese patients before and after an intervention of bariatric surgery

Shewale JB, Correa AM, Brown EL, Leon-Novelo LG, Nyitray AG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Roth J, Vaporciyan AA, Swisher SG , Sepesi B