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The plasmid was linearized by the restriction enzyme (Thermo Fisher, Waltham, MA, USA) and used as the template to produce mRNA with T7 High Yield RNA Transcription kit (#DD4202, Vazyme)
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Abrupt discontinuation without a management plan can lead to deterioration in blood glucose control, potentially increasing the risk of hyperglycaemia and long-term diabetic complications
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The SURMOUNT-OSA phase 3 clinical trial examined the use of tirzepatide for the treatment of moderate-to-severe obstructive sleep apnea in adults with obesity
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