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Purging: It happens during the initial detoxification process, which makes you break out as the body flushes out toxins

K., & Yakutseni, P

Of importance, a current phase II clinical trial NCT03872427 is analyzing the therapeutic response of the advanced solid tumors to CB-839/telaglenastat depending on the mutations in genes regulating the antioxidant system such as neurofibromatosis-1 gene (NF1), Kelch-like ECH-associated protein 1 KEAP1, nuclear factor erythroid 2-related factor 2 (NRF2), and serine/threonine kinase 11 (STK11)

doi: 10.1038/nrclinonc.2015.105 83 LuHOuyangWHuangC

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J Biol Chem (1977) 252:12506