Furthermore, zebrafish models provide tractable systems for studying hostpathogen interactions, offering novel perspectives on the regulation of inflammatory networks (Torraca and Mostowy, 2018)
[DOI] [Google Scholar] 5.Simoni R.D., Hill R.L., Vaughan M
doi: 10.1111/j.1365-2982.2011.01796.x 18 BlackA
Statistical analysis ImageJ 1.44P was used for quantitative analysis of immunoblotting, and GraphPad Prism 8.0 (GraphPad Software, CA, USA) was used for data statistics and mapping
Adaptive mitochondrial remodeling following dual SHP2/MEK inhibition is confirmed in vivo To determine whether the observed metabolic properties following SHP2/MEK inhibition prove true in vivo, we treated KPC mice, monitored the pancreatic tumor volume via magnetic resonance imaging (MRI), and collected tumor interstitial fluid (TIF)
Envisaged treatment to modulate macrophages phenotype