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Mild abdominal discomfort is common with GLP-1 agonists and usually improves over time

Elevated lactate concentrations within the tumor microenvironment can activate GPR81 receptors located on the cytoplasmic membrane of cells, subsequently facilitating MCT1-mediated lactate uptake (57,58)

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Tirzepatide can reduce your appetite and make you less inclined to drink fluids, especially if youre feeling nauseated or experiencing mild GI side effects

[4] Ibid., p