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It is well established that overweight and obesity increase a persons risk of cardiovascular events, but the concept of treating obesity to reduce cardiovascular complications has been hampered by lack of evidence that lifestyle or pharmacologic interventions for overweight or obesity improve cardiovascular outcomes, says Dr

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10.3389/fonc.2023.1251561 167 WangL.LiuY.DuT.YangH.LeiL.GuoM.et al (2020)

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FGF19, in turn, via the gallbladder FGFR4-Klotho smooth muscle receptor, promotes gallbladder relaxation and the refilling with dilute hepatic bile

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