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Although liver- and kidney-targeted therapies have been predominant, future objectives should emphasize extrahepatic delivery utilizing sophisticated carriers such as LNPs or dendrimers modified with targeting moieties like peptides or antibodies, which can enhance specificity, internalization, and therapeutic efficacy

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doi: 10.1126/scitranslmed.aaf2362 13 Bull-OttersonL.BacaS.SaydahS.BoehmerT

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