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Diagnstico se realiza a travs del examen fsico, dermoscopia, biopsia de la lesin y otras tcnicas como mapeo de ganglios linfticos y biopsia del ganglio linftico centinela, TC (tomografa computarizada), exploracin con PET (tomografa por emisin de positrones), imgenes por resonancia magntica con gandolino (RM), anlisis de sangre