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Reviews have proposed that GLP-1 signaling, changes in adipose-derived stem cells, oxidative stress, and dermal remodeling could affect collagen support and skin architecture beyond the mechanical loss of facial fat

And are they worth trying

Patients with a history of gastrointestinal conditions such as acid reflux, irritable bowel syndrome, or gastroparesis should be especially cautious when starting GLP-1 medications

GLP-1s in the news Most recent: Weight Loss Drugs Like Ozempic Are Lowering the U.S

If a patient asks if its safe to take if they think they are at risk for macular degeneration, I think these results might help physicians suggest it is likely safe to take in that situation, says Young

And that doesnt even take into account cardiovascular disease and diabetes