In harmony with GSH and vital enzymatic antioxidants, AsA can provide an important redox environment, essentially required for various defence-related pathways such as controlling the expression of defensive genes through the stimulation of the NPR1 (Nonexpresser of Pathogenesis-Related protein 1), cell wall strengthening, regulatory transcription factors, alteration of defence inducing hormone-signalling systems [152]
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ROS-mediated NLRP3 inflammasome activation in brain, heart, kidney, and testis ischemia/reperfusion injury
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HY enriched in NF-B signaling pathway, MAPK signaling pathway and TNF signaling pathway (Fig