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J Cell Mol Med 24(24):1440514414 Das B, Sarkar C, Rawat VS, Kalita D, Deka S, Agnihotri A (2021) Promise of the NLRP3 inflammasome inhibitors in in vivo disease models

Because only around 1% of an oral dose is absorbed (versus ~89% for an injection), a much larger oral dose is needed to deliver an equivalent amount of semaglutide into the bloodstream