In conclusion, pyroptosis in tubular cells plays an important role in the progression of DKD, and the underlying detailed mechanism requires further investigation
2 Majority of patients were treated with standard of care 1,2,n,o Summary of medication at baseline (N=3533) 1,2 Select CV and CKD baseline characteristics (N=3533) 1,2 n At baseline patients in FLOW were receiving standard-of-care background therapy, including a maximum tolerated label dose of a RAAS-blocking agent including an ACE inhibitor or an ARB, unless such treatment was contraindicated or not tolerated
This process allows similar cases to be handled collectively, streamlining discovery and pretrial proceedings
doi: 10.1016/j.scienta.2018.10.007 28 DanevaA.GaoZ.Van DurmeM.NowackM
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Kawakami, T., Kitaura, J., Xiao, W