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In fact, there is a well-documented counter-regulatory reduction in metabolic rate in both humans (31, 32) and rodents (30, 33) treated with GLP-1R agonists for extended periods due to the reduction food intake

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doi: 10.1038/aps.2011.149 138 AlmutairiMAl BatranRUssherJR

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Published online May 22, 2025 DOI: 8,858 View 196 Download 1 Web of Science 1 Crossref Abstract PDFSupplementary MaterialPubReader ePub Background Obesity is a rapidly increasing global health issue, which is associated with glucose and insulin resistance

Mounjaro also mimics another hormone called glucose-dependent insulinotropic polypeptide (GIP)