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Strategies to minimize reactions include rotating injection sites consistently to avoid repeated trauma to the same area, ensuring the solution is at room temperature before injection (cold injections can increase irritation), injecting slowly rather than quickly, and using a smaller gauge needle for less tissue trauma

The improvements in reaction time are similar in healthy adults who underwent a visual colour discrimination task after the same dose of L-theanine (200 mg) and a comparable dose of caffeine (160 mg) alone

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A quality-of-life study in healthy adults supplemented with Lentinex beta-glucan of shiitake culinary-medicinal mushroom, Lentinus edodes (Agaricomycetes)

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