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MIN6B1 cells were incubated overnight with serum-free media plus 25 mM glucose and 0.5 mM palmitate/BSA 100 nM agonists, fixed, processed with the In Situ Cell Death Detection Kit, TMR red (Roche), and imaged as above

bone density data pending

On the other hand, in terms of weight loss, available data suggest that the combination of the 2 agonists had a synergistic effect (table 1) [10]

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Research Highlights Superior Glycemic Control: Tirzepatide lowers HbA1c by up to 2.4% in people with type 2 diabetes, surpassing standard therapies 3,5