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Pregnant individuals should avoid berberine entirely

Additionally, thermosensitive nanogels and stimuli-responsive nanocarriers that respond to pH or glucose levels have been proposed for precision-controlled GLP-1 delivery, enabling intelligent drug release based on glycemic fluctuations

Carriers are not affected by the disorder

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The FDA prescribing information reports diarrhea in 30% of patients treated with the 2.4 mg injection compared with 16% on placebo in the weight-reduction trials