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The results demonstrated that TSF-DET1 sufficiently pulled down MBP-Ube2e1-3, but not Ube2d3 (Fig.3A)

As it does that, it produces other metabolites, including 4PY

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doi: 10.1016/j.jdermsci.2015.05.003 56 Dell'AnnaMLOttavianiMBelleiBAlbanesiVCossarizzaARossiLet al

This is critical data to have before seeking FDA approval

Rat tissue sections were pretreated for 15 min with HIER at 95 C in ER2 (Leica) followed by a 15-min protease treatment and then hybridized with rat-specific probes to detect mRNA transcripts for CALCR (477798), PRLH (1301288-C2) and GLP1R (315228-C3