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Shortest paths analysis Shortest-path analyses were conducted using the PathLinker Cytoscape App 101 with the following parameters: an unweighted, undirected network and the target set (GLP1R/GCGR/GIPR/GCG/GIP), and sources defined as genes linked to signaling pathways from curated databases

1,2,3 The trial also showed greater weight loss with tirzepatide

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Timing mattersstarting during remission is generally safer than during active flare periods