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PMC Cognitive Function and Neurological Research Robillard JM, et al

While semaglutide is highly effective for weight loss, metformin has modest weight-reducing effects, primarily through its role in stimulating the production of N-lactoyl-phenylalanine, an appetite-suppressing metabolite generated in the intestine 61

Then, nuclear and cytoplasmic intensity values were normalized within each independent experiment by dividing the values of each individual measurement by the mean total intensity across all conditions, thereby normalizing for inter-experimental variability while preserving relative differences between ECM conditions

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