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Document the clinical rationale per patient in the chart itself: why this compound, why this patient, what you expect to monitor

Current evidence is reassuring

This can be due to COMT, MTR or MTRR genetic mutations which help the body convert B12 into its active forms for use at the enzymatic and cellular level

PMID: 35472176

THP and MDA levels were measured using commercial kits following manufacturer instructions, while SOD activity was determined via inhibition of pyrogallol autoxidation

Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials