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High cortisol also impairs insulin sensitivity and disrupts blood sugar regulation, working directly against the mechanisms that make GLP-1 medications effective

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N Engl J Med 1992;327:1426e33

In addition, a composite endpoint comprised of participants who achieved an HbA1C level 6.5% and weight loss of at least 10%, was assessed

However, as with any supplement, it's recommended to consult with a healthcare professional before starting to ensure it aligns with your personal health needs

Side effects are significantly affecting quality of life Some people experience persistent side effects that do not improve over time