Cancer cells are full of glutathione
Similar concerns have been seen with lipid outcomes with an increase in total cholesterol after cessation of semaglutide to near pretreatment levels and loss of around two-thirds of the benefit in triglycerides, while positive changes in LDL-C and HDL-C were more modest but appeared more durable (Table 2) [73]
[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Major J.M., Laughlin G.A., Kritz-Silverstein D., Wingard D.L., Barrett-Connor E
Further, GLP-1RAs block the adhesion of monocytes to endothelium induced by oxidized LDL via extracellular signal-regulated kinase (ERK) 5-Kruppel-like factor (KLF)2 signaling pathway to prevent endothelial permeability [107, 108]
Kwon YH, Fingert JH, Kuehn MH, Alward WL
Gas Chromatography Mass Spectrometry Aided Diagnosis of Glutathione Synthetase Deficiency