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Beyond just increasing airway resistance, obesity also affects metabolism, inflammation, and muscle tone, all of which influence breathing stability at night

22.67 38.62 mL, p = 0.265), or gastric volume per kilogram (GV/kg: 0.15 0.37 vs

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2022 Jun 28;14(13):2674

Diabetes Stud

This self-inhibition at high doses diminishes degradation efficiency, confounds the dose-response relationship, and complicates efficacy predictions, while potentially elevating the risk of systemic side effects (Fig