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Among them, the cytosolic enzyme nicotinamide N-methyltransferase (NNMT) has been newly discovered to regulate the levels of nicotinamide precursors required for NAD+ biosynthesis, and therefore plays a crucial role in regulating the NAD+ salvage pathway and cellular metabolism

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We examined their physicochemical properties, secondary structures, and mechanisms of action, and compared them with the peptides in the AMP database

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