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95% CI 0.772.42) ( 4.3 Post natal factors (INFANT) 4.3.1 Breastfeeding Breastfeeding is protective of asthma/wheeze from 0 to 2 years at which time the protective effect seems to wane ( Breastfeeding data in weaker- designed studies might have a recall bias or difference in breastfeeding data might be attributable to the duration of breastfeeding

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We extend the scope of our systems to a range of ring substitution patterns 11 and 12 and heterocycles 13 , providing a chemical toolbox for bioisosteric replacement of naphthalene, (iso)quinoline and quinazoline