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At 40 weeks, mean body weight changes were 7.5 kg with 10 mg and 8.8 kg with 15 mg doses, compared to 1.6 kg with placebo

Blood sugar, blood pressure, and lipid improvements measurable

Constipation: On the flip side, some individuals may experience constipation while taking GLP-1 medications, particularly if they have a history of gastrointestinal issues or a low-fiber diet

Clarifying the mechanisms underlying these effects requires deeper exploration of tirzepatides distinct physiological actions beyond glucose control