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Key finding: Unprecedented mitochondria-to-nucleus communication pathway for metabolic adaptation
Tyni T, Pihko H, Kivela T: Ophthalmic pathology in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency caused by the G1528C mutation
Figure 5 ALC reduced cholesterol synthesis by decreasing SREBP2 levels in Huh-7 hepatocytes To elucidate the cellular mechanisms underlying ALCs cholesterol-lowering effects, ALC reduced the plasma TC in mice and decreased the hepatic SREBP2 and HMGCR levels
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Add nutrient-dense foods first, such as lean proteins, beans, Greek yogurt, eggs, vegetables, fruit, whole grains, nuts, and healthy fats