[6] [9] According to NICE guidance (NG28), GLP-1 receptor agonists are recommended as part of a comprehensive treatment strategy for type 2 diabetes that includes dietary modification, increased physical activity, and other glucose-lowering therapies when appropriate
For example, patients using Mounjaro have experienced greater reductions in HbA1c compared to those on Semaglutide, making it a compelling option for individuals struggling to manage their diabetes with traditional therapies
Managing side effects often involves lifestyle adjustments and communication with healthcare providers
It works on three hormone pathways: GIP, GLP-1 and glucagon
30,31 Due to the degradation of peptide-based drugs by proteolytic enzymes, the low permeability of intestinal epithelium, and the low pH of the gastrointestinal tract, oral administration of semaglutide is challenging
About this article Cite this article Zhou, L., Wei, A., Pan, C