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The most common adverse reactions reported in clinical trials include nausea, vomiting, diarrhea, abdominal pain, and constipation, occurring in more than 5% of patients

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Insulin-like growth factor binding proteins IGFBP3, IGFBP4, and IGFBP5 predict endocrine responsiveness in patients with ovarian cancer

Others may be drawn to the culture of optimisation, where the pressure to appear in a certain manner or remain productive and energetic takes primacy