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Any blood in urine warrants immediate medical attention since even microscopic amounts can signal serious conditions like cancer that are most treatable when caught early

PubMed PMID: in vitro and in vivo

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Zonulin (Z01/2), Claudin, Occludin and the JAM family proteins regulate how permeable the paracellular space is i.e., intestinal permeability or leaky gut. In this state of increased intestinal permeability or hyperpermeability, organisms, toxins, proteins or pathogens which are normally not absorbed are able to pass through the enterocyte intestinal layer and barrier and enter the body