High activity of MBOAT1 and MBOAT2 uses monounsaturated fatty acids (MUFAs) rather than PUFAs for acylation of lysophospholipids, thus lowering the PUFA content in phospholipids and ferroptosis susceptibility (173)
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Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity
Supplementation with synbiotic kefir (goat milk kefir with probiotics) in high-fat, high-fructose (HFHF) diet-fed rats lowered HbA1c levels, improved insulin production, and enhanced overall metabolic health compared with non-supplemented kefir (Nurliyani et al., 2022)
however, loss of function mutations in HSL cause FLD in humans (142) and partial lipodystrophy with age (204, 205)
Growth hormone responses to GRF 1-29 in patients with primary hypothyroidism before and during replacement therapy with thyroxine