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However, it should be noted that other free amino acids, which are present in the blood serum at total 3 mM concentration 42 , can also form tight ternary complexes with Cu(II)-His 45

h , Fold change (log 2 ) in indicated whole cell or ER metabolites from ER-tag HEK293T cells treated with glucose deprivation compared to glucose repletion

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Blankenship JM, Chipkin SR, Freedson PS, Staudenmayer J, Lyden K, Braun B