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These amino acids stimulate specialized cells in your small intestine to release GLP-1, sending powerful fullness signals to your brain while also helping regulate blood sugar after a meal

In: Advances in Pharmaceutical Biotechnology

If you are extremely sensitive and find that taking the supplement on a completely empty stomach causes mild nausea, clinical evidence suggests pairing it with a very small, light snack (such as a few bites of fruit or a cracker) can mitigate digestive discomfort while still preserving the stability of the acetylated molecule

Antiinflammatory actions of glucagon-like peptide-1based therapies beyond metabolic benefits Chi Kin Wong, et al