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Provincial healthcare systems increasingly recognize the connection between obesity treatment and cardiovascular cost savings

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Several treatments that can therapeutically target these pathways have been tested in preliminary clinical trials

Research on GLP-1 receptor agonists shows that gradual tapering of blood levels occurs over several days, so one-day timing variations fall within the normal window of therapeutic action

doi: 10.1152/ajpendo.00004.2012 46 DeyAChandrasekaranK

Farnesoid X Receptor-Mediated Cytoplasmic Translocation of CRTC2 Disrupts CREB-BDNF Signaling in Hippocampal CA1 and Leads to the Development of Depression-Like Behaviors in Mice