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Histopathology and immunohistochemistry confirm structural preservation, reduced edema/demyelination, and restored NRF2 and p-AKT expression, providing strong preclinical rationale for semaglutide as a candidate therapy for CIPN

In a 1998 selectivity study, ipamorelin did not change FSH, LH, prolactin, or TSH levels

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At this concentration, a 2.5 mg dose equals 0.50 mL (50 units on an insulin syringe)

Consider staying at 8mg if weight loss is satisfactory and side effects are manageable

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