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In other words, we cant directly extrapolate recommendations for vegans from the trials in the graphs above except to know that 500 g per day is enough for vegans based on Crane, 1998

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Pernicious Anemia: This is an autoimmune disorder where the body mistakenly attacks a protein in the stomach called "intrinsic factor." Without this protein, you simply cannot absorb B12 from food, making injections a lifelong necessity

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1,2 Off-Label Medications Off-label therapies, including amitriptyline, fluoxetine, gabapentin, cyclobenzaprine, and tramadol, have been shown to reduce patients fibromyalgia pain