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In the TSHR-immunized murine model of Graves disease, Treg depletion (particularly CD25) induced thyroid lymphocytic infiltrates with transient or permanent hypothyroidism (19.2)

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While Zepbound itself does not directly cause yeast infections, several factors associated with weight loss treatment may create conditions that could potentially influence susceptibility to Candida overgrowth

However, start slow and gradually increase intensity as your body allows

10.1038/nrm3311 48 HarrisK

Evening dosing considerations Some people prefer evening dosing because morning nausea is a common side effect during the first weeks