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(2014) documented that the compound remains stable in aqueous buffers at pH 4.57.4 for at least two weeks even at 60C stress conditions, though oxidative stress represents its greatest vulnerability
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found that acetaminophen causes concentration-dependent neuronal death in vitro at concentrations that are reached in human plasma during acetaminophen overdose, and are reached in the cerebrospinal fluid of rats for 3 h following doses that are below those required to induce acute hepatic failure in rats
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