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The 5-session protocol outperformed a previous 3-session protocol (26.5% vs 10%, p = 0.0025)

Yet, many people cannot

Escalation phase breakdown The standard protocol starts low and increases every four weeks to minimize gastrointestinal side effects that rapid dose escalation can cause

Patients should follow the personalized regimen given by the provider

In the BLOOM trial, patients treated with lorcaserin achieved highly significant and absolute weight loss in 1 year, and continuous treatment with lorcaserin over 2 years helped two-thirds of the patients maintain a weight loss of 5% or greater [83]

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