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Nature (2012) 485:2425.10.1038/nature11011 12 SandersSJMurthaMTGuptaARMurdochJDRaubesonMJWillseyAJet alDe novo mutations revealed by whole-exome sequencing are strongly associated with autism

The brain and nervous system are especially prone to free-radical-induced damage, due to their highly oxygenated organ function 40 and low catalase activities 41

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In addition, posttranslational modification and proteolytic cleavage have shown to produce additional forms of STAT1 and STAT3 (100)

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